P
c
 
@ڎɖ߂
͔̔wiΐFŕ\Ă܂B
2005/6/07

Ȃj@ʍɏ]Aʎ܂B
@̑ṔAґ΍ɂ‚Ăł܂B
@ߔN̏qЉɂāAґ΍̏dv͊Ɍ䏳m̂Ƃł܂BAJȂ\QOOSNx̐lԓvł́Ao͉ߋŒɂȂAPl̏UɎYގq̐͑ONƓP.QXlŁAόNjQX.U΁AQV.W΂ƉߋōXV悤ł܂B܂܂qiłƂ@Iȏ󋵂ɂ܂B
@q̌ƂāA܂Ŏdƈ玙̗Ƃϓ_A{͂̑΍G[vVG[vȂǂ{Ă킯łAoቺɎǂ߂邱Ƃ͍̂ƂłĂȂ󋵂ł܂B
@Ƃ낪AߔNq̐VJjYƂāAt[^[݂̑傫N[YAbvĂ܂B҂̌ٗp߂ẮAƗǂ܂肷钆AAoCgp[gȂǂ]XƂt[^[ANxSł悻QPVlƔ\Ă܂A傫ȎЉƂȂĂ܂B̑Əo͂悻ႵĂ܂B
@UQ̓ǔVɂ܂ƁAt[^[Â炢R͌oϗ͂̒ႳɂƏĂ܂BŇٗpu΁Aq͐[ɂȂƂĂ܂BŁAqǂEqĉvɊÂA琬x΍i@̂S{sĂ܂B
@̃t[^[݂̖̑AƐ[Ȃ̂NƎҁAȂ킿AEɂ‚AwZ@ւɂĂAAJɌ̓IȓĂȂj[gƌĂ΂҂݂̑łB邽߂ɉĂȂƂƂ́Aɐeꂩ̎xȂɂ͐łĂȂ킯łA̐ی\RɂȂ킯ŁAt[^[̑q̈łƓlɁAߔÑj[g̑傫ȎЉƂȂĂ܂BߔÑj[g̖̑́A҂̐S̖肪悤łBj[g̖ɂ́A^wXƎq̂Ƃ̃LA炪dvȂ̂ł͂Ȃł傤B
@ŁAPԖڂɁAj[g̎ԂƂ̑΍ɂ‚Ăf܂B
@ɁAґ΍ƂāAlވ琬ɂ‚Ăf܂B
@lވ琬́A҂ΏۂƂlވ琬ړIł͂܂񂪁Ał͓Ɏ҂̐lވ琬ΏۂƂāÅ̊p̎dɂ‚Ăf܂B
@݂̐lވ琬̐x́AP񂫂̉ʂȖړIłpł܂B̍ōz͂Pɂ‚TO~łAďȉ߂zł͂܂񂵁AɖɗĂƎv܂Ac̖P~ɑ΂AŜ̗p󋵂͂ǂȂ̂ł傤Bp鐧x́Alވ琬̗v󋵂ɑΉłĂł傤BPOAQO̎҂ɓ{␢E\”\ނꂽƂA̐lނ^ɂӂ邳ƉFsĂƂAIɎxlވ琬̂悤ȁALȊp̂ł͂Ȃł傤B̐lނA邢͐EIɗLȐlނɈƂAXFšւɂȂ킯łB
@ŁAlވ琬ɂ‚āA̔FƗLȊp@ɂ‚Ăf܂B
@ɁȂQA҂΂Ȃ߂̐̒ɂ‚Ăł܂B
@҂΂Ȃ߂ɍsɊ撣Ă邩f܂BAmgj̎M̕sɂȂĂ܂Bmgj̎Mɂ‚ẮA̎gɖ肪oAsoƂ킯ł܂BȂčςނ̂Ȃ略Ȃƍl鍑Â͂Ȃ悤Ɏv܂BAĂ҂炷΁AĂȂl̂߂ɂmgjێĂĂ悤Ȃ̂ŁA[܂B
@FsɖڂĂ݂܂傤Bׂŋgp͕҂̋`ł܂BȂlĂA̐xێĂƂA͕ĂlɕS񂹂Ă̂łAȂl͕sȂǂƂÂ̂ł͂ȂAĂl̂Ɠł܂BƂƂ̂Ɠ܂Błł́AEłɂ͏dłdg݂ɂȂĂ܂Bsł͂ǂ󋵂Ȃ̂ł傤B҂΂Ȃ̒ɂ邽߂ɁAs͂ǂ撣Ă܂B
@ŁAPԖڂɁAsŁAscZgpANیAwZHȂǂ̑ؔ[ɂ‚āAؔ[̏󋵂Ƃ̑΍ɂ‚Ăf܂B
@܂Aؔ[Ă҂ɑ΂A[҂ƌł낤͂Ȃƍl܂BɎx\͂Ȃ略ӎv̂ȂȉЂlɑ΂Äꕔ~⎁̌\ƂΉ‚̂ؔ[h肾ĂɂȂ̂ł͂Ȃƍl܂A䌩f܂B
@QԖڂɁAscZ̓iƐی󋋎ǐ擾̕ωɂ‚ĂǂΉĂ̂Af܂B
@s̒ɎscZɓɂ͂ǂ炢Ɩ₢킹Ăl܂B܂AیlɁAی炤ɂ͂ǂ炢Ǝ₳l܂B葱̖₳ꂽ̂ł͂܂BîƂ𕷂ꂽ킯łBscŹA{AᏊ҂̏Z‹ێ邽߂ɌĂꂽ̂ŁAƂA݁AZmۉ”\Ȑlɔẑł͂܂B܂AیłBǂ炦邩ł͂ȂAȂΐǂɂێłȂl̂߂ɁA@ŕۏႳĂƂ̍Œ̕IŌNȐێ錠ۏႷ邽߂ɂ鐧xłBscZ̐x̕ی̐xA{l̐x͊iiɌサ܂B
@ŁA̐x{̖ړIǂɉ^p邱Ƃ͂ƂĂdvȂƂłƍl܂BɁA@ɊÂ葱̖肾NAAɉ^pĂȂA܂ƂɊ撣lɑ΂AĈłBs΁Asɂ͐҂΂Ă̂ł͂ȂƂO܂BۂɁAscZɓĂlɑ΂A̎Ԓ͂ǂȂĂ̂ł傤BیĂl̐Ԃ͎i𓾂ƂƕῶȂAƎԒ͂Ă̂ł傤Af܂B
@܂Aی̐x́A󋋎i҂̈ꐶ̖ʓ|邽߂̂̂ł͂܂Bx΍͂ǂȂĂ̂ł傤Af܂B
@ŌɁAhƃpg[̍ۂ̔펞̑Ήɂ‚Ăf܂B
@SIɎs̎hƈӎ܂‚‚钆AƂRɎšpԂɂhƃpg[̃XebJ[\܂BpŎsEsړrhƂ̖ڂ点ƂӖƁAԂs𑖂邾łhƂ̌ʂ҂łƎv܂B
@܂A鎩ł́Aq̖hƃpg[Ȃǂ̎IȖhƊn܂Ă悤łBꎩ̂͑ϗLӋ`ŌʓIłƎv܂ALɑꍇAsȆΉ͂ǂȂĂ̂f܂B
@ȏŁAdォ̎I܂B

   
sicvNj@Pč䎿ɂ܂B
@䎿̑PAґ΍ɂ‚āAP_̎NƎҁij[gj̎ԂƂ̑΍ł܂AJȔŝQOOSNŘJoϔł́ANƎҁAj[gɊY҂́AQOORN_łTQlƂĂ܂BɂẮANƎ҂ɑ΂铭ӗ~̟{Ê߁AҎmnoiƂn݂Am{҂̌傪n܂Ƃł܂B
@܂AsƂ܂ĂALA`yу^wX̑kƖs̎NJ҃LA`xEJkƂɉ債ARŗBFsΘJNق{{݂ƂČ肵Ƃł܂BƂANƎґ΍ɂ‚܂ẮA֌W@ւƘAgAgł܂肽ƍlĂ܂B
@ɁAQ_̐lވ琬ł܂AFsӂ邳Ɛlވ琬ɂ‚܂ẮA{s̎YƁAoρAAAȂǂ̊eɂĎwIȖʂL\Ȑlނ琬邱ƂړIɐݒûł܂BQNx̂PTNԂłUW̏tA܂܂ȕ̐lވ琬xɗLɊpĂƂł܂B
@ȂAߔNAЉoϏ傫ωAsj[YlĂ钆Å̂LȊp@ɂ‚āAAĂ܂肽ƍlĂ܂B
@ɁA䎿̑QA҂΂Ȃ߂̐̒ɂ‚āAP_̎sŁAscZgpANیAwZHȂǂ̑ؔ[ŁA܂AȂؔ[󋵂Ƃ̑΍͂Ƃq˂ł܂A܂Asłɂؔ[̏󋵂ɂ‚܂ẮAPTNx̌ZŐ\グ܂ƁAؔ[҂̐⏊݂̕sȂǂɂQS,SOO~̕s[z𐶂ʁAؔ[Jzz͖PXW,QOO~ƂȂĂ܂B
@ɁAscZgp̕s[z͖QWO~Aؔ[Jzz͖PP,POO~ANی̕s[z͖PR,WOO~Aؔ[Jzz͖PTQ,UOO~AwZH̕s[z͖QO~Aؔ[Jzz͖XX~ƂȂĂ܂B
@܂Aؔ[̑΍Ƃ܂ẮAdbɂ‘EÍAƒKɂ[twpIɍsĂ܂AɁA͂Ȃ[tȂ҂ɑ΂܂ẮAsłɂ‚Ă͍Œ@EnŖ@̋KɊÂAsYAŒȂǂ̍A葱Ȃǂ̑ؔ[sĂ܂B
@܂AscZgṕAuscZnɊւvjvɊÂAZ̖n߂Ă܂B
@Nی́Aʏ̔یҏ؂ɂāAZیҏ؂⎑iؖ̌tsĂ܂B
@݂̎ЉoϏAɌ‹ɂ܂Asłɂ܂ẮAgĎ⒥ẘpȂǂɂǍʂĂĂƂłAƂAϋɓIȎ[΍𐄐iĂ܂肽ƍlĂ܂B
@ɁAČ̈ꕔ~⎁̌\ƂƂł܂A݁Asœ̑ؔ[ɂAsT[rX~Ȃǂ̑[u͍sĂ܂񂪁AOɑؔ[hϓ_AƎ̗Z≺rݔ̗q⋋̐\݂ɂāAsł̑ؔ[ȂƂvƂĂ܂B
@܂ANیɂ܂ẮANی@̋KɊÂAiؖ̌t҂ɂ́AیtƂĂ̌t͍s킸AҕƂĂƂł܂B
@ȂǍ\ɂ‚܂ẮAlی̊ϓ_Â݂ƂlĂ܂B
@ɁAQ_̎scZiƐی󋋎ǐ擾̕ωŁA܂AA̎Ԓ̏󋵂̂q˂ł܂AscZɂ‚܂ẮAANA\ĂۂɁAёS̏ؖoĂAƈٓ̔cɓw߂ĂƂł܂B
@܂AsݎҁAZ̓]݋yѓ̌̏nȂǂɊւ󋵂ɂ‚āAZǗl̕񍐂ɂAԒsƂŕsh~ɓw߂ĂƂł܂BƂAscZ̓KȊǗɓw߂Ă܂肽ƍlĂ܂B
@یɂ‚܂ẮAی\̍ۂɁAAYA}{`҂̏󋵓\Ă炤ƂƂɁAZ@ցAیЁA}{`ғɐ\e̎ԒsǍʂɊÂAی̗vۂ肵Ă܂B܂AیJnAɊւĂ̐ŖAAJ̉”ۂɊւĂ̕aԒA}{`ҒAY󋵒̎ԒsAی̓K{ɓw߂ĂƂł܂B
@ɁAC̐ی󋋎҂ւ̎x΍ł܂A{sɂ܂ẮAی@{s^c{j̒ŏd_ڂ߁AAJ”\Ȏ҂ɑ΂AJw̓O}{`Ғ̓OȂǁAsƎ̓_ƂĎgł܂܂BPVNxJȂi߂Ă鐶ی󋋐т̏󋵕͂ŁAX̎󋋎҂̎ԂɍxsxvOɂ‚ĂA{Ă܂肽ƍlĂ܂B
@ɁA䎿̑RAhƃpg[̍ہA펞̑Ή͂Ƃq˂ł܂AߔNASIɋƍ߂钆ASESȂ܂Âɑ΂s̋C^NX܂ĂĂAs̊enɂ܂ĂAq̌Ȃǂ̎IȖhƊLĂ܂B
@̂悤ȏ󋵂̒AhƑ΍̎g݂ƂāAšpԂɖhƍLpu}Olbg𒣂‚As̖hƈӎ̍g}ƂƂɁAEɖhƈӎĐE𐋍sg݂NRn߂Ƃł܂B
@펞ɑꍇ̑Ήɂ‚ẮAEll̔fɂ܂AK؂ȑΉł悤hƑ΍Ɏgł܂肽ƍlĂ܂B
@ȏŁAd̓قI܂B
 
Ȃj@኱ςčĎ₳ĂƎv܂B
@PQ,OOOlɑ΂ATQlƂ́A䗦ł΁APvZ܂ƁAlPWl̉FsƂVWOlɂȂ킯łBš݂̐ی󋋐тP,WOOтłÃj[g̐̋ЂɂȂƐVɂĂ̂FsɂĂ͂܂Ǝv܂B
@ԍȂ̂́Ãj[g̐NӂĂƂƂƎv܂Bd̏̈ӗ~ȂAĂȂj[g̑̓t[^[ȏɐ[ȖŁA̖{l͂AYƂoς̏AЂĂ͎Љ̈ێWɂƂċyڂe͏܂BЉIɖLɂȂāAqȂĐHׂĂ邾ł͂ȂAeqɁAlɂȂĂLȐ܂ŕۏႵĂ̂肾Ǝv܂B
@‚܂Ãj[ǵ̖AЉ̏łǂ̂悤ɓ`Ă̂ł傤BЉwȂǂł̖グꂽ悤ȂƂ͂܂ł傤B
 
畔idaFNj@܂B
@Љ̏ō܂Ńj[gƂꂩg񂾂Ƃ͂܂񂪁AЉ̊ϓ_\グ΁Aƒׂ͂Ă̋̏o_łA͂̊bIȎ\͉͂ƒɂĂ|ƌĂA{słЉ̎g݂ɂĂ܂܂Ȍ`ŎxsĂ܂B
@ȏł܂B
 
Ȃj@肪Ƃ܂B
@@QVɁAׂĂ̍͋ΘJ̌LA`𕉂ƂȂĂ킯łA@ɏĂ邩ł͂ȂAq̂ƂAlɂȂdƂƂwZ̏ŋĂȂ΂ȂȂł͂Ȃƍl܂AwZ̏ŏj[gɂȂȂ߂̋Ƃ̂͂Ă̂ł傤B
 
璷iOchNj@܂B
@k̔BiKɉ܂āAΘJρAEƊςĂ邱Ƃ͏dvłA݁AewZŋȁAAʊAIȊwK̎ԓł悭邽߂̋ɎgłƂł܂B
@ɖ{sɂ܂ẮAȊwȂ̃LA琄inw莖Ƃ̎w󂯂܂āAwAHcAeƏAیғ̋͂𓾂ȂAĚwK𒆐SƂLAeRZAvXZɂĐiĂƂł܂BƂA֌W@֓ƘAgăLA̐iɓw߂Ă܂肽ƍlĂ܂B
@ȏł܂B
 
Ȃj@肪Ƃ܂B
@̉FɂARwZȊwȂ̃LA̎w󂯂āANxЉwȂǂʂăLAɎgłƏĂłA{AwZŋȏȊOŊw΂Ȃ΂ȂȂϏdvȂƂłƎv܂̂ŁAЈꕔ̓ʂȂƂƂĂł͂ȂAq̂Ƃ瓭Ƃ̏dvɂ‚ċĂĂƎv܂B
@j[g̖̉ɌāAAǂ̂悤Ȏ肾ĂsƂĂ̂AЉŜĂ肾ƌƎv܂BN҂Ƃ̐ړ_LAӋ`y悤ɂ邱Ƃ̑؂厖Ǝv܂B
@AsɈڂƂƂ͌قNJȒPł͂܂BC^[lbgŌłAj[gɂ͂S‚̌^ƏĂ܂̂ŁAƔI܂BPԁAL[^AЉIŋyIAy΂Ƃ^CvBQԖڂ^AЉƂ̊֌WzAĂ܂^CvBRԖڂ݌^AAEOɍlł܂AslĂ܂^CvBSԖڂ‚܂^Aꂽ͏AẾAXɂ߁AMr^CvBƂA͘J􌤋EC@\Ƃ͂Ă܂B
@ȂS‚̃^CvɕނĂ̂j[gȂłAt[^[Ȃǂ̘b܂ƁANƎ҂̗ɂ͕sɂƂ̗̍p}⑦͎uƎv܂A҂̏AJӎ̕ωЉP̕seĂ̂ł͂Ȃł傤B҂rWlX}i[R~jP[V\͂𖁂΁A̗p̉”\܂ƂāA܂łɐEƌP\͂AJӗ~̌ɂ˂炢iPZ~i[Ȃǂ̑΍d_IɍuĂĂ܂B
@A炪ʂグĂƂ͌_ł͌Ȃł傤BQOORNx̃t[^[̐QPVlƁAONWlӂĂƂƂRƎv܂BԂɂ́Aƃt[^[ƕč̗p킹Ƃ܂łBґ̓w͕sł傤A͂̈ӎvȂΐʂɂ͂‚ȂȂƎv܂B
@܂āAj[ĝ͓ӗ~Ƃʂ̖łāAXɉߍׂΉ͓RƂāA΍̒gɂٗp̖̘g𒴂AYƁAЉƂĂ̕Lg݂߂Ǝv܂BЉŜŔFςĂKvƎv܂B
@ŁAoϊEAYƊE̕ł̃j[gɑ΂F̖L߂ĂƂƂŁAƂHcƂAƂɑ΂āAj[g̖̍l悤ȋ@Ƃ̂͂܂ł傤Af܂B
 
oϕiR͌Nj@j[g΍ɂ‚܂ẮAɂẮAҏAEZ^[Ƀj[gkݒuAґ΍Aٗp΍ɂ‚Ďgł܂B
@{sɂ܂ẮAC^[VbvR[fBl[^[̐xɂAHcȂǂƘAgAƁAwȂǂ̃j[YcAK؂ȃC^[Vbṽ}b`Ô߂݂̑̏񋟂⒲sĂƂł܂A킹āAj[g΍܂߂ٗp̊gȂǂ̂肢ȂǂAs̊Ƃɑ΂Am[sĂƂł܂B
@ȏł܂B
 
Ȃj@̎Ƃ𓾂āAFsΘJNقŎNJ҂̃LAJEZOs\łƐقǂ̓قł킯łAj[g̐lłȂA̎NJ҂̐_IȎxƂȂ悤ɁAΘJNقψ̎{݂ƂĂłȂANJ҂ɃLA`xJkƖƂĊpĂ悤ɁA悭`ĂƂƂ킹ėv]Ă܂B
@̐lވ琬łAȐlɎĂ݂łA\̐x悭mȂlA̐x̂悭悤ƂĈȑO̖ŁAƎsɊp`邱Ƃn߂Ȃ΂ȂȂ悤ȋCĂ܂Bs̍LɖNWڂĂ̂́AC‚Ă͂łAxPɂ‚TO~炦Ƃ]ɂb܉߂āA\łȂȂn[hɎvĂ܂̂܂BPTNԂłUWƂ̂Ȃ̂킩܂񂪁AŜł͂ǂ̂炢傪ł傤B
 
siRNj@܂B
@ߋ̌o܂͂܂SׂĂ܂񂪁Ao猾܂ƁAقƂǗƂƂƂ͂ȂāAg̐RāAA\̈ȑOɉcƂ`Ŏނ邱Ƃ悤łǂAې\ꂽAgɂ‚ĐRāA኱ӌƂ܂A{IɁÂ܂܊{IɒʂĂƂƂł܂B
@ȏł܂B
 
Ȃj@SŁAEŒʗpȈނFsɂƂAl牞傪ȂƂ܂ȂłAN҂ĂƂƂɂȂƁAlA傪ȂlłAۂ͉^ěʔȂǂČ\Ă̂ł͂ȂƂƂz܂B
@Ⴆ΂̗Ō܂ƁAq̏шłˁA͏wZwN̂ƂAsAmőSōZx̑ŗDĂ܂BCOȂ񂩂ꂩǂǂs邻ł܂BAیāA@܂AȂƎv܂BꂩADAtĂ܂A݂PS΂łBGNg[łS΂̂ƂɗDāAwZPNőSPʂɂȂĂ܂Bقɂ܂񂨂邩܂BwZwNɓ{ꂾƂAǂ܂Ő̂z‚܂񂪁Aqւ̐lވ琬x̏ꍇA܂ł̉Fs̐lވ琬̂ł͍ȂȂĂ񂶂ȂȂƂC܂B
@܂␢EIȖIɂȂ僊[ÕC`[IȂǂɓĂ͂߂Ă݂܂ƁAAFsňނ͓{琢EɉH΂āAAFƂꏊł܂܈Ă邯ǂAFʉ߂Ă܂܂BȂAFsɂƂāAꗬ̐lq̂ƂɉFsňƁAɍڂ邾ʼnFsւɎvƎv܂Bs炷΁A̐Sɂ͉FsĂƂC΂Ǝv܂Bނɑ΂Aq̂Ƃ̎x͑厖Ǝv̂ŁAЂlވ琬̎x̂lĂƗv]Ă܂B
@ɁAƏԂς܂āAԍŌ̖hƃpg[̍ۂ̔펞̑Ήɂ‚ĂȂłAhƃuU[qɎĂ܂ÂƂʎsɂǂm点Ă̂ł傤B펞ɂǂΉsɂ肢Ă邩ƂƂ厖Ǝv܂A肢͂Ăł傤B
 
璷iOchNj@n̕Xւ̂肢ł܂ǂAn̕Xɂ́AewZwZAnł̉ł肢Ă܂ǂAȂw̎mɓw߂Ă܂肽ƍlĂ܂B
@ȏł܂B
 
Ȃj@uU[Ă邩SƂƂŕЂÂȂ悤ɂ낵肢܂B
@s̐E̖hƃpg[̂ƂȂłAhƃpg[̍Œɔ펞ɑAXɑΉƂƂł܂ÂƂƂ̂ǂ̂ƂAȂƂlƎvłBŁAΉ}jAĂ悤ȂƂKvłƎ͎vłAقǂ̓ق̒̓K؂ȑΉƂ̂́AǂΉ̂ƂĂ̂ł傤Af܂B
 
siRNj@܂B
@c܂悤ɁÂт̃pg[̎Ԃւ̒‚ɂ‚܂ẮAn̕񂢂Ȍ`Ŏq̎Ƃ撣ĂƁAŌpԂʼn킯łÂƂɓ\tĎsɐ`ƂƂA[ƂƂ܂AɁAs̐E傫ȁA̖ڂŌĂƂƂӎIɂƂƂ͔ɂ͂厖Ȃ낤ƂƂĒĂ킯łB
@ÂƂɁAAc񂪌܂悤ɁAႠAǂ邩ƂƂłA{Iɂ͌x@ɘAƂƒxꉞlĂ܂񂪁A͂s̐EłAȂƂlĂƎv܂ǂAPl̏ꍇ܂A邢͂QlRlĂꍇ܂āA͗Ջ@ςɑΉĂƁB܂łs̐E납Ԃ^]ƂA`ł̖hƑ΍lĎdĂȂƂƂł܂B
@ȏł܂B
 
Ȃj@̖ŌXɂǂ낱ƂȂƂ͂ȂȂƎvŁAAXebJ[̎̎ԂɒĂ邱ƂYĂ܂悤ȁAƂȂ悤ɁAsÂƂɖhƂ̖ڂ点Ă񂾂ƂƂAoYȂ悤ɂēw߂ĂƂƂ肢܂B
@ɁApg[̌͂ꂮ炢ɂ܂āAQԖڂ̐҂΂Ȃ߂̐̒ɂ‚Ăf܂B
@PTNx̎sł̑ؔ[󋵂ɂ‚Ă͂Ƃf܂AߋƂTNԂ́APSNxȑO̕ƂƎv܂B
 
iacYNj@ߋTNԂ̑ؔ[󋵂ł܂AƂPOO~PʂłĂ܂BPPNxؔ[JzzPWX,XOO~Aꂩ畽PQNxAPXU,QOO~APRNxAQOV,QOO~APSNxAQPR,VOO~APTNxAPXW,QOO~ƂȂĂ܂B
@ȂAs[̏󋵂Ƃ܂ẮAPPNxPS,VOO~APQNxPS,XOO~APRNxPU,POO~APSNxPT,XOO~APTNxQS,SOO~APTNx͑^Ƃ̓|Y̐Zɔ኱ƑĂƂ󋵂ɂ܂B
@ȏłB
 
Ȃj@ANP܁AZ疜~ÓAƂƂ́Asł̖A͂PAO.TłANx͂PƁBAzlAܔN܂΁AwZPŒ‚炢̋zɂȂĂ킯łBz͏ȂƂ̂͂ЂƂ‚킩Ǝv܂Ȃؔ[̑΍ƂĂ̓‘ƂƂAƂĂƂƂȂłȀ󋵂Ƃ̂́AʂƂ̂͂ǂӂɂȂĂ邩Af܂B
 
iacYNj@słɂ‚܂ẮAPTNxZŐ\グ܂ƁA̕PTNx̌Nېłł܂ANېŕł́AŜ̂WWɑQOPT,OOO~Aɂ‚܂ẮA[Ɏ[tĂƂł܂AĉPQɂ‚ẮA͂肻̔[ɔ[tꂸAؔ[΍̕KvĂƂł܂B
@ɂ‚܂ẮA܂‘EÍƂ܂ĂPTV,OOO̒ʒm𔭑Aɂ́ǍT,UOO̓dbÍAĂɁAR,VOO̖K[twsƂł܂B
@̌ʁANېŕɂ‚܂ẮA[̔[tQPV,OOO~ƂӂɂȂĂ܂̂ŁA[΍Ƃ܂ẮANȂ̐ʂ𓾂Ăł͂ȂƂӂɍlĂ܂B
 
Ȃj@肪Ƃ܂B
@悻PAsłQQOłAP̌JzAؔ[Jz钆ŁAςP߂ؔ[΍􂪕KvƂƂɂȂĂ܂B͂ς肩Ȃ傫ȐŁANꐶ撣ĂȂƁAƔ[߂ĂlA݂Ȃ[߂ĂƂCɂȂȂƁAĂ҂[܂̂ŁAƂ낵撣āAؔ[΍͂ĂƂӂɎv܂B
@scZ̎gpɊւČ܂ƁA̓‘ƂA͌ŕ܂傤B̊Ȃǂ̌ʂƂ̂͂ǂȂĂ܂ł傤B
 
y،zi{NjNj@܂B
@scZgpɊւ̂ɂ‚܂āAPTNxZŐ\グ܂ƁA[Ɏ[tĂAŜ̂WPɑSX,UOO~ł܂BĉPXɂ‚܂ẮAؔ[΍̕KvƂł܂B
@܂āANԂłW,VOO̕ɂ‘EÍAQ,SOO̓dbÍAɁAT,VOO̖K[twsʁAW,OVO~[tA̐ʂꂽ̂ƍlĂ܂B
@ȏł܂B
 
Ȃj@Nی̌͂̕ǂȂłB
 
siRNj@܂B
@PTNxZŐ\グ܂ƁAŜ̂WSɑSPT,OOO~[Ɏ[tĂ܂ǂAcPUɂ‚܂ẮAؔ[΍􂪐Ă܂B̂߁AWW,OOO̕ɂ‘EÍPOOɋyԓdbÍA邢͂SWɋyԋxEԂ̑k̊J݂K⊈A邢͂̑APRl̏ɂIȖK⊈ƂĂ܂B̌ʁANxɂ‚ẮASP,TOO~[tĂ܂B܂ʂɁAߔNxłǂAW,POO~ƂƂŁA킹ĖSX,UOO~炢΂肪Ă܂BȂ̐ʂ͂̂ƍlĂ܂B
@ȏł܂B
 
Ȃj@ȍÑ肷̂ȂȂςƎvłAP‚̕@ƂāÄꕔ~ƂǍ\ƂƂŎ₳ĂłÁA悻̎sőؔ[Ҍ\ŒƂƂAؔ[Ƃ悻łႪ܂āAƂł̂ȂƂƂłf킯łB̒ŁȀɂ‚Ă͗L҂ł‚ؔ[RƌlیR̈ӌɊÂƁAƂŏ\ꂽʁAႪłƂfẮAlی@ɂ͒GȂƔfƂӂɏĂ킯łAFsŁAقǂ̌䓚قł́AlیɊւĂƂƂōlĂȂƂӂɌꂽłAFsłƂꂽ悤ȂƂ͂ł傤B
 
iacYNj@͂ɂ炸[tȂXɑ΂܂ẮAsdŌ䓚ق܂悤ɁA@ɊÂȂǂ̑ؔ[ϋɓIɍsĂĂ܂āA̐ʂ킸ł‚‚Ƃł܂B
@̂߂ɁAsł̔[tɐӂĂȂ[Ŏ҂̎̌\ɂ‚܂ẮA܂œɌƂ͂܂񂪁Al񂠂邢͂̎`Ɛ[֘A܂̂ŁA̍ۂɂ͐TdȑΉKvƍl܂BMdȌ񌾂܂AƖ̒SƂ܂ẮAiKł́ȂOɑؔ[ɂZp͂邢͌”\́AEll̔\͂̌Ɣ[ʼnۂƂĂ̑gD̋ɓw߂āA܂͔[ł̌}Ă悤ɓw߂Ă܂肽ƂӂɍlĂ܂B
 
Ȃj@̂Slی@{sĂ܂Alی@ƂƂ̖@̒ŁAӂ́A̕ɔ邱ƂɊւĂꂪ^pƂƂ͂ƎƔ[Ȃ킯ŁA_A\ƂƂ΂茾Ă킯ȂāAi‚ƁAs炩̂ΉĂ邼ƂŒAsłؔ[ɁAȂłˁAȂlȂāA猾Ă̂́A\͂ȂAȁAȂȕΏۂɌĂ܂̂ŁA̕ӂ̂Ȃ悤ɁA̕ӂĂ悤ɂ肢܂B
@QԖڂ̎scZ̓iƐی̎󋋎i̍̌擾̕ωɂ‚Ă̍ĎȂłA̎scZ̎ԒsʂƂ̂͂ǂł傤B
 
y،zi{NjNj@܂B
@PUNx܂łɏZǗl̕񍐂܂߁Asݎ҂RTAs҂UƂȂĂ܂BŜłSPƂȂĂ܂B̓҂ɑ΂ďZ̖nsĂ܂ÂPPɂ‚܂Ă͎IɑދAɉȂPQɑ΂܂ẮA@I[uɂZ̖n݋߂Ă܂B@I[u܂߂ďZ̖n߂ĂƍlĂ܂B
@ȏł܂B
 
Ȃj@ƁAl͂ƎĂƁAꂩw͂낵肢܂B
@󋋊Jn̐ی󋋎҂̎Ԓ̌ʂƂ̂͂ǂ̂Af܂B
 
Nklivۏ͌Nj@܂B
@یJn̊e풲Kwɂ‚Ăǂ̂悤ɂĂ邩Ƃ䎿₾낤Ǝv܂AیJńA̐т̏󋵂ĂĖKv肵AvIɖK₵Ă܂B̒ŁAт̕鏔蓙ɂ‚ĎwAsĂƂł܂B
@܂Aa󒲍ɂ‚܂ẮAZvg̓_邢͎厡ォ̈ӌAƂƂɁAsňϏĂ܂ォ̈ӌsȂåmFsĂƂł܂B
@܂AAJɊւĂA\̒o̗s߂ȂASт̉ېŏ󋵂̒sāA̔cɓw߂ĂƂł܂B
@ȏł܂B
 
Ȃj@܂Aقǂ܂悤ɁÁA҂ƂAōĂ؂̂ĂƂAƂĎ͍₵Ă킯ł͂܂B̒ŁAςꂵA{ɋꂵl邽߂ɂ́Aς\ZƂς́Asv܂A܂BӖŁAςꂵӂĂl񂶂ȂƁAs̐l^̖ڂŎvĂ邩ɂ́Aςقǂ̂mgj̎MƈꏏɁAȂčςނ񂾂略ȂAƂl鐢̒ƁAϐ҂΂鐢̒ƂӂȕsKȌʂɂȂĂ܂܂̂ŁAƂȂ悤ɂƂāAsĂĂƂƂmFĎ₳ĂĂ܂B
@Ⴆ΁AeqɎYقƂǏāAqe̖ʓ|ȂAی炦킯łBāA̎q̓j[gɂȂāAe̎YH‚ԂĂ܂ƂƂl킯łBтm炸A͐ی炤\RɂȂĂ܂ƁBƂAہAʂ̐lAȂ΂΂Ȃ悤ȂƂۋN蓾鍡̐xƁA̐̒Ax񂶂ȂāA̒̐ĺAƂ蓾鐢̒ƂӂȂƂŁA͐҂΂ĂƂӂɏ񂶂ȂāA҂΂Ȃ̒ƂƂŌ킹ĂĂ܂B
@ꂩ܂cŝSNĂƁA撣ĂāA҂΂Ȃ̒̂߂ɈꐶĂƂ肢܂āA̎I܂B
 
 
 
 
@ڎɖ߂